Myeloid Endoplasmic Reticulum Resident Chaperone GP96 Facilitates Inflammation and Steatosis in Alcohol‐Associated Liver Disease

Cellular stress–mediated chaperones are linked to liver macrophage activation and inflammation in alcohol‐associated liver disease (ALD). In this study, we investigate the role of endoplasmic reticulum (ER) resident stress chaperone GP96/HSP90B1/GRP94, paralog of the HSP90 family, in ALD pathogenesi...

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Detalles Bibliográficos
Autores principales: Ratna, Anuradha, Lim, Arlene, Li, Zihai, Argemi, Josepmaria, Bataller, Ramon, Chiosis, Gabriela, Mandrekar, Pranoti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8279472/
https://www.ncbi.nlm.nih.gov/pubmed/34278167
http://dx.doi.org/10.1002/hep4.1713

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8279472/
https://www.ncbi.nlm.nih.gov/pubmed/34278167
http://dx.doi.org/10.1002/hep4.1713

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