Cargando…

Myeloid Endoplasmic Reticulum Resident Chaperone GP96 Facilitates Inflammation and Steatosis in Alcohol‐Associated Liver Disease

Cellular stress–mediated chaperones are linked to liver macrophage activation and inflammation in alcohol‐associated liver disease (ALD). In this study, we investigate the role of endoplasmic reticulum (ER) resident stress chaperone GP96/HSP90B1/GRP94, paralog of the HSP90 family, in ALD pathogenesi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ratna, Anuradha, Lim, Arlene, Li, Zihai, Argemi, Josepmaria, Bataller, Ramon, Chiosis, Gabriela, Mandrekar, Pranoti
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8279472/ https://www.ncbi.nlm.nih.gov/pubmed/34278167 http://dx.doi.org/10.1002/hep4.1713

Ejemplares similares

Endoplasmic reticulum stress in hepatic steatosis and inflammatory bowel diseases
por: Guo, Beichu, et al.
Publicado: (2014)

Identifying New Epigenetic Drivers of Liver Fibrosis
por: Argemi, Josepmaria, et al.
Publicado: (2018)

GP96: safeguarding Treg
por: Zhang, Yongliang, et al.
Publicado: (2015)

Targeting Epigenetic Mechanisms to Alleviate Alcoholic Steatosis
por: Mandrekar, Pranoti
Publicado: (2020)

Alcohol and Cancer: Mechanisms and Therapies
por: Ratna, Anuradha, et al.
Publicado: (2017)

Gut homeostasis and regulatory T cell induction depend on molecular chaperone gp96 in CD11c(+) cells
por: Hua, Yunpeng, et al.
Publicado: (2017)

Murine but Not Human Basophil Undergoes Cell-Specific Proteolysis of a Major Endoplasmic Reticulum Chaperone
por: Liu, Bei, et al.
Publicado: (2012)

Interaction of Toll-Like Receptors with the Molecular Chaperone Gp96 Is Essential for Its Activation of Cytotoxic T Lymphocyte Response
por: Liu, Weiwei, et al.
Publicado: (2016)

Regulation of the Expression of Chaperone gp96 in Macrophages and Dendritic Cells
por: Wolfram, Lutz, et al.
Publicado: (2013)

Serum Acylcarnitines Associated with High Short-Term Mortality in Patients with Alcoholic Hepatitis
por: Gao, Bei, et al.
Publicado: (2021)

The neuroprotective potential of endoplasmic reticulum chaperones
por: McLaughlin, Todd, et al.
Publicado: (2015)

Chaperone gp96 mediates ER-α36 cell membrane expression
por: Hou, Junwei, et al.
Publicado: (2015)

Molecular Chaperone GRP94/GP96 in Cancers: Oncogenesis and Therapeutic Target
por: Duan, Xiaofeng, et al.
Publicado: (2021)

Influences of Transporter Associated with Antigen Processing (TAP) on the Repertoire of Peptides Associated with the Endoplasmic Reticulum–resident Stress Protein gp96
por: Arnold, Danièle, et al.
Publicado: (1997)

Expression of Endoplasmic Reticulum Chaperones in Cardiac Develop-ment
por: Papp, Sylvia, et al.
Publicado: (2008)

Endoplasmic Reticulum Chaperones and Their Roles in the Immunogenicity of Cancer Vaccines
por: Graner, Michael W., et al.
Publicado: (2015)

Perturbation of the Relative Contribution of Molecular Chaperones in the Endoplasmic Reticulum
por: Totani, Kiichiro, et al.
Publicado: (2020)

Dual topology of co-chaperones at the membrane of the endoplasmic reticulum
por: Daverkausen-Fischer, Lea, et al.
Publicado: (2021)

Endoplasmic Reticulum Chaperones in Viral Infection: Therapeutic Perspectives
por: Kohli, Evelyne, et al.
Publicado: (2021)

The regulatory role of endoplasmic reticulum chaperone proteins in neurodevelopment
por: Sun, Hongji, et al.
Publicado: (2022)

Reduced Serum Sphingolipids Constitute a Molecular Signature of Malnutrition in Hospitalized Patients With Decompensated Cirrhosis
por: Rachakonda, Vikrant, et al.
Publicado: (2019)

Extracellular gp96 is a crucial mediator for driving immune hyperactivation and liver damage
por: Guan, Zeliang, et al.
Publicado: (2020)

Chemical Chaperones to Inhibit Endoplasmic Reticulum Stress: Implications in Diseases
por: Jeon, Jae-Ho, et al.
Publicado: (2022)

Identification of gp96 as a Novel Target for Treatment of Autoimmune Disease in Mice
por: Han, Jung Min, et al.
Publicado: (2010)

Iron affects Ire1 clustering propensity and the amplitude of endoplasmic reticulum stress signaling
por: Cohen, Nir, et al.
Publicado: (2017)

Liver-specific ceramide reduction alleviates steatosis and insulin resistance in alcohol-fed mice
por: Correnti, Jason, et al.
Publicado: (2020)

The endoplasmic reticular heat shock protein gp96 is transcriptionally upregulated in interferon-treated cells
Publicado: (1994)

Chaperone-mediated coupling of endoplasmic reticulum and mitochondrial Ca(2+) channels
por: Szabadkai, György, et al.
Publicado: (2006)

MicroRNA-210 and Endoplasmic Reticulum Chaperones in the Regulation of Chemoresistance in Glioblastoma
por: Lee, Derek, et al.
Publicado: (2015)

The Endoplasmic Reticulum Chaperone GRP170: From Immunobiology to Cancer Therapeutics
por: Wang, Hongxia, et al.
Publicado: (2015)

MANF antagonizes nucleotide exchange by the endoplasmic reticulum chaperone BiP
por: Yan, Yahui, et al.
Publicado: (2019)

Endoplasmic reticulum chaperone genes encode effectors of long-term memory
por: Chatterjee, Snehajyoti, et al.
Publicado: (2022)

Induction of Foxp3 and activation of Tregs by HSP gp96 for treatment of autoimmune diseases
por: Xu, Yuxiu, et al.
Publicado: (2021)

Gp96 Peptide Antagonist gp96-II Confers Therapeutic Effects in Murine Intestinal Inflammation
por: Nold-Petry, Claudia A., et al.
Publicado: (2017)

Abnormally expressed ER stress response chaperone Gp96 in CD favours adherent-invasive Escherichia coli invasion
por: Rolhion, Nathalie, et al.
Publicado: (2010)

Regulation of protein O-glycosylation by the endoplasmic reticulum–localized molecular chaperone Cosmc
por: Ju, Tongzhong, et al.
Publicado: (2008)

Molecular Chaperones in the Yeast Endoplasmic Reticulum Maintain the Solubility of Proteins for Retrotranslocation and Degradation
por: Nishikawa, Shuh-ichi, et al.
Publicado: (2001)

136 HIV-1 Nef regulates activity of endoplasmic reticulum chaperone calnexin
por: Jennelle, Lucas, et al.
Publicado: (2014)

Endoplasmic Reticulum Chaperones and Oxidoreductases: Critical Regulators of Tumor Cell Survival and Immunorecognition
por: Gutiérrez, Tomás, et al.
Publicado: (2014)

BiP, an endoplasmic reticulum chaperone, modulates the development of morphine antinociceptive tolerance
por: Dobashi, Tamae, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_6dm93uretb8hl30b2ohsk5jma7