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A Study of an 8-Aminoquinoline-Directed C(sp(2))–H Arylation Reaction on the Route to Chiral Cyclobutane Keto Acids from Myrtenal

[Image: see text] This work outlines a synthetic route that can be used to access chiral cyclobutane keto acids with two stereocenters in five steps from the inexpensive terpene myrtenal. Furthermore, the developed route includes an 8-aminoquinoline-directed C(sp(2))–H arylation as one of its key st...

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Detalles Bibliográficos
Autores principales: Pourghasemi Lati, Monireh, Ståhle, Jonas, Meyer, Michael, Verho, Oscar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8279478/
https://www.ncbi.nlm.nih.gov/pubmed/34042431
http://dx.doi.org/10.1021/acs.joc.1c00774