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Synthesis of 4-O-Alkylated N-Acetylneuraminic Acid Derivatives
[Image: see text] The synthesis of 4-O-alkyl analogues of N-acetylneuraminic acid (Neu5Ac) and the scope of the reaction are described. Activated alkyl halides and sulfonates and primary alkyl iodides give products in useful yields. The utility of the methodology is exemplified using a thiophenyl Ne...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8279483/ https://www.ncbi.nlm.nih.gov/pubmed/34138565 http://dx.doi.org/10.1021/acs.joc.1c00235 |