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The interplay between matrix deformation and the coordination of turning events governs directed neutrophil migration in 3D matrices

Neutrophils migrating through extravascular spaces must negotiate narrow matrix pores without losing directional movement. We investigated how chemotaxing neutrophils probe matrices and adjust their migration to collagen concentration ([col]) changes by tracking 20,000 cell trajectories and quantify...

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Detalles Bibliográficos
Autores principales: François, Joshua, Kandasamy, Adithan, Yeh, Yi-Ting, Schwartz, Amy, Ayala, Cindy, Meili, Ruedi, Chien, Shu, Lasheras, Juan C., del Álamo, Juan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8279509/
https://www.ncbi.nlm.nih.gov/pubmed/34261650
http://dx.doi.org/10.1126/sciadv.abf3882