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The interplay between matrix deformation and the coordination of turning events governs directed neutrophil migration in 3D matrices
Neutrophils migrating through extravascular spaces must negotiate narrow matrix pores without losing directional movement. We investigated how chemotaxing neutrophils probe matrices and adjust their migration to collagen concentration ([col]) changes by tracking 20,000 cell trajectories and quantify...
Autores principales: | François, Joshua, Kandasamy, Adithan, Yeh, Yi-Ting, Schwartz, Amy, Ayala, Cindy, Meili, Ruedi, Chien, Shu, Lasheras, Juan C., del Álamo, Juan C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8279509/ https://www.ncbi.nlm.nih.gov/pubmed/34261650 http://dx.doi.org/10.1126/sciadv.abf3882 |
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