αβ/γδ T cell lineage outcome is regulated by intrathymic cell localization and environmental signals

αβ and γδ T cells are two distinct sublineages that develop in the vertebrate thymus. Thus far, their differentiation from a common progenitor is mostly understood to be regulated by intrinsic mechanisms. However, the proportion of αβ/γδ T cells varies in different vertebrate taxa. How this process...

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Detalles Bibliográficos
Autores principales: Aghaallaei, Narges, Dick, Advaita M., Tsingos, Erika, Inoue, Daigo, Hasel, Eva, Thumberger, Thomas, Toyoda, Atsushi, Leptin, Maria, Wittbrodt, Joachim, Bajoghli, Baubak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8279519/
https://www.ncbi.nlm.nih.gov/pubmed/34261656
http://dx.doi.org/10.1126/sciadv.abg3613

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8279519/
https://www.ncbi.nlm.nih.gov/pubmed/34261656
http://dx.doi.org/10.1126/sciadv.abg3613

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