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Aged-related Function Disorder of Liver is Reversed after Exposing to Young Milieu via Conversion of Hepatocyte Ploidy

Previous study showed that senescent hepatocytes from aged liver could be rejuvenated after repopulated in the young recipient liver. The proliferative capacity of hepatocytes was restored with the senescence reversal. However, it is unknown whether metabolic and homeostatic function of aged liver,...

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Detalles Bibliográficos
Autores principales: Liu, Qinggui, Chen, Fei, Yang, Tao, Su, Jing, Song, Shaohua, Fu, Zhi-Ren, Li, Yao, Hu, Yi-Ping, Wang, Min-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8279529/
https://www.ncbi.nlm.nih.gov/pubmed/34341705
http://dx.doi.org/10.14336/AD.2020.1227