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Premature Senescence of T-cells Favors Bone Loss During Osteolytic Diseases. A New Concern in the Osteoimmunology Arena

Cellular senescence is a biological process triggered in response to time-accumulated DNA damage, which prioritizes cell survival over cell function. Particularly, senescent T lymphocytes can be generated prematurely during chronic inflammatory diseases regardless of chronological aging. These senes...

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Detalles Bibliográficos
Autores principales: González-Osuna, Luis, Sierra-Cristancho, Alfredo, Rojas, Carolina, Cafferata, Emilio A, Melgar-Rodríguez, Samanta, Cárdenas, Angélica M, Vernal, Rolando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8279535/
https://www.ncbi.nlm.nih.gov/pubmed/34341698
http://dx.doi.org/10.14336/AD.2021.0110