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Cardiac Glycoside Ouabain Exerts Anticancer Activity via Downregulation of STAT3

Cardiac glycosides are plant-derived steroid-like compounds which have been used for the treatment of cardiovascular diseases. Ouabain, a cardiotonic steroid and specific Na(+)/K(+)-ATPase inhibitor, has been rediscovered for its potential use in the treatment of cancer. However, the cellular target...

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Detalles Bibliográficos
Autores principales: Du, Jie, Jiang, Lijun, Chen, Fuqiang, Hu, Huantao, Zhou, Meijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8279743/
https://www.ncbi.nlm.nih.gov/pubmed/34277430
http://dx.doi.org/10.3389/fonc.2021.684316