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Cardiac Glycoside Ouabain Exerts Anticancer Activity via Downregulation of STAT3
Cardiac glycosides are plant-derived steroid-like compounds which have been used for the treatment of cardiovascular diseases. Ouabain, a cardiotonic steroid and specific Na(+)/K(+)-ATPase inhibitor, has been rediscovered for its potential use in the treatment of cancer. However, the cellular target...
Autores principales: | Du, Jie, Jiang, Lijun, Chen, Fuqiang, Hu, Huantao, Zhou, Meijuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8279743/ https://www.ncbi.nlm.nih.gov/pubmed/34277430 http://dx.doi.org/10.3389/fonc.2021.684316 |
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