Cargando…

NLRR1 Is a Potential Therapeutic Target in Neuroblastoma and MYCN-Driven Malignant Cancers

Receptor tyrosine kinases (RTKs) receive different modulation before transmitting proliferative signals. We previously identified neuronal leucine-rich repeat 1 (NLRR1) as a positive regulator of EGF and IGF-1 signals in high-risk neuroblastoma cells. Here, we show that NLRR1 is up-regulated in vari...

Descripción completa

Detalles Bibliográficos
Autores principales: Takatori, Atsushi, Hossain, MD. Shamim, Ogura, Atsushi, Akter, Jesmin, Nakamura, Yohko, Nakagawara, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8279747/
https://www.ncbi.nlm.nih.gov/pubmed/34277416
http://dx.doi.org/10.3389/fonc.2021.669667