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Folding of cohesin’s coiled coil is important for Scc2/4-induced association with chromosomes

Cohesin’s association with and translocation along chromosomal DNAs depend on an ATP hydrolysis cycle driving the association and subsequent release of DNA. This involves DNA being ‘clamped’ by Scc2 and ATP-dependent engagement of cohesin’s Smc1 and Smc3 head domains. Scc2’s replacement by Pds5 abro...

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Detalles Bibliográficos
Autores principales: Petela, Naomi J, Gonzalez Llamazares, Andres, Dixon, Sarah, Hu, Bin, Lee, Byung-Gil, Metson, Jean, Seo, Heekyo, Ferrer-Harding, Antonio, Voulgaris, Menelaos, Gligoris, Thomas, Collier, James, Oh, Byung-Ha, Löwe, Jan, Nasmyth, Kim A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8279761/
https://www.ncbi.nlm.nih.gov/pubmed/34259632
http://dx.doi.org/10.7554/eLife.67268