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Sensitive Detection of Single-Nucleotide Polymorphisms by Solid Nanopores Integrated With DNA Probed Nanoparticles

Single-nucleotide polymorphisms (SNPs) are the abundant forms of genetic variations, which are closely associated with serious genetic and inherited diseases, even cancers. Here, a novel SNP detection assay has been developed for single-nucleotide discrimination by nanopore sensing platform with DNA...

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Detalles Bibliográficos
Autores principales: Wu, Ling Zhi, Ye, Yuan, Wang, Zhi Xuan, Ma, Die, Li, Li, Xi, Guo Hao, Bao, Bi Qing, Weng, Li Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8279778/
https://www.ncbi.nlm.nih.gov/pubmed/34277589
http://dx.doi.org/10.3389/fbioe.2021.690747