Nrf2 Pathway Ameliorates Bladder Dysfunction in Cyclophosphamide-Induced Cystitis via Suppression of Oxidative Stress

OBJECTIVE: To investigate the protective effect and molecular mechanism of nuclear factor E2-related factor 2 (Nrf2) pathway in interstitial cystitis (IC). METHODS: We established a mouse model of IC by cyclophosphamide (CYP) in wild-type mice and Nrf2 gene knockout mice. We examined the histologica...

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Detalles Bibliográficos
Autores principales: Ni, Bin, Chen, Zhengsen, Shu, Le, Shao, Yunpeng, Huang, Yi, Tamrat, Nebiyu Elias, Wei, Zhongqing, Shen, Baixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8279868/
https://www.ncbi.nlm.nih.gov/pubmed/34306306
http://dx.doi.org/10.1155/2021/4009308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8279868/
https://www.ncbi.nlm.nih.gov/pubmed/34306306
http://dx.doi.org/10.1155/2021/4009308

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