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Loss-of-function mutations in IFNAR2 in COVID-19 severe infection susceptibility

Recent COVID-19 (coronavirus disease 2019) host genetics studies suggest enrichment of mutations in genes involved in the regulation of type I and type III interferon (IFN) immunity in patients with severe COVID-19 infection. We performed whole-genome sequencing analysis of samples obtained from pat...

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Detalles Bibliográficos
Autores principales: Smieszek, Sandra P., Polymeropoulos, Vasilios M., Xiao, Changfu, Polymeropoulos, Christos M., Polymeropoulos, Mihael H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Ltd on behalf of International Society for Antimicrobial Chemotherapy. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8279933/
https://www.ncbi.nlm.nih.gov/pubmed/34273592
http://dx.doi.org/10.1016/j.jgar.2021.06.005