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Acute Kidney Injury in Severe COVID-19 Has Similarities to Sepsis-Associated Kidney Injury: A Multi-Omics Study

OBJECTIVE: To compare coronavirus disease 2019 (COVID-19) acute kidney injury (AKI) to sepsis-AKI (S-AKI). The morphology and transcriptomic and proteomic characteristics of autopsy kidneys were analyzed. PATIENTS AND METHODS: Individuals 18 years of age and older who died from COVID-19 and had an a...

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Detalles Bibliográficos
Autores principales: Alexander, Mariam P., Mangalaparthi, Kiran K., Madugundu, Anil K., Moyer, Ann M., Adam, Benjamin A., Mengel, Michael, Singh, Smrita, Herrmann, Sandra M., Rule, Andrew D., Cheek, E. Heidi, Herrera Hernandez, Loren P., Graham, Rondell P., Aleksandar, Denic, Aubry, Marie-Christine, Roden, Anja C., Hagen, Catherine E., Quinton, Reade A., Bois, Melanie C., Lin, Peter T., Maleszewski, Joseph J., Cornell, Lynn D., Sethi, Sanjeev, Pavelko, Kevin D., Charlesworth, Jon, Narasimhan, Ramya, Larsen, Christopher P., Rizza, Stacey A., Nasr, Samih H., Grande, Joseph P., McKee, Trevor D., Badley, Andrew D., Pandey, Akhilesh, Taner, Timucin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mayo Foundation for Medical Education and Research. Published by Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8279954/
https://www.ncbi.nlm.nih.gov/pubmed/34425963
http://dx.doi.org/10.1016/j.mayocp.2021.07.001