Distinct roles of Fto and Mettl3 in controlling development of the cerebral cortex through transcriptional and translational regulations

Proper development of the mammalian cerebral cortex relies on precise gene expression regulation, which is controlled by genetic, epigenetic, and epitranscriptomic factors. Here we generate RNA demethylase Fto and methyltransferase Mettl3 cortical-specific conditional knockout mice, and detect sever...

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Detalles Bibliográficos
Autores principales: Du, Kunzhao, Zhang, Zhen, Zeng, Zhiwei, Tang, Jinling, Lee, Trevor, Sun, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8280107/
https://www.ncbi.nlm.nih.gov/pubmed/34262022
http://dx.doi.org/10.1038/s41419-021-03992-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8280107/
https://www.ncbi.nlm.nih.gov/pubmed/34262022
http://dx.doi.org/10.1038/s41419-021-03992-2

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