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Isoflurane impairs oogenesis through germ cell apoptosis in C. elegans

Anesthetic isoflurane has been reported to induce toxicity. However, the effects of isoflurane on fecundity remain largely unknown. We established a system in C. elegans to investigate the effects of isoflurane on oogenesis. Synchronized L4 stage C. elegans were treated with 7% isoflurane for 4 h. D...

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Detalles Bibliográficos
Autores principales: Zhang, Tao, Ni, Cheng, Li, Cheng, Lu, Pan, Chen, Dan, Dong, Yuanlin, Whetstine, Johnathan R., Zhang, Yiying, Xie, Zhongcong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8280124/
https://www.ncbi.nlm.nih.gov/pubmed/34262087
http://dx.doi.org/10.1038/s41598-021-93737-0