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Intracellular lipid droplet accumulation occurs early following viral infection and is required for an efficient interferon response

Lipid droplets (LDs) are increasingly recognized as critical organelles in signalling events, transient protein sequestration and inter-organelle interactions. However, the role LDs play in antiviral innate immune pathways remains unknown. Here we demonstrate that induction of LDs occurs as early as...

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Detalles Bibliográficos
Autores principales: Monson, E. A., Crosse, K. M., Duan, M., Chen, W., O’Shea, R. D., Wakim, L. M., Carr, J. M., Whelan, D. R., Helbig, K. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8280141/
https://www.ncbi.nlm.nih.gov/pubmed/34262037
http://dx.doi.org/10.1038/s41467-021-24632-5