Cargando…
Intracellular lipid droplet accumulation occurs early following viral infection and is required for an efficient interferon response
Lipid droplets (LDs) are increasingly recognized as critical organelles in signalling events, transient protein sequestration and inter-organelle interactions. However, the role LDs play in antiviral innate immune pathways remains unknown. Here we demonstrate that induction of LDs occurs as early as...
Autores principales: | Monson, E. A., Crosse, K. M., Duan, M., Chen, W., O’Shea, R. D., Wakim, L. M., Carr, J. M., Whelan, D. R., Helbig, K. J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8280141/ https://www.ncbi.nlm.nih.gov/pubmed/34262037 http://dx.doi.org/10.1038/s41467-021-24632-5 |
Ejemplares similares
-
Lipid droplet density alters the early innate immune response to viral infection
por: Monson, Ebony A., et al.
Publicado: (2018) -
Lipid Droplet Motility Increases Following Viral Immune Stimulation
por: Monson, Ebony A., et al.
Publicado: (2021) -
Lipid droplets and lipid mediators in viral infection and immunity
por: Monson, Ebony A, et al.
Publicado: (2021) -
The interferon stimulated gene viperin, restricts Shigella. flexneri in vitro
por: Helbig, K. J., et al.
Publicado: (2019) -
Host upregulation of lipid droplets drives antiviral responses
por: Monson, Ebony A., et al.
Publicado: (2021)