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Smoking accelerates renal cystic disease and worsens cardiac phenotype in Pkd1-deficient mice
Smoking has been associated with renal disease progression in ADPKD but the underlying deleterious mechanisms and whether it specifically worsens the cardiac phenotype remain unknown. To investigate these matters, Pkd1-deficient cystic mice and noncystic littermates were exposed to smoking from conc...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8280209/ https://www.ncbi.nlm.nih.gov/pubmed/34262092 http://dx.doi.org/10.1038/s41598-021-93633-7 |