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Spontaneous apoptosis of cells in therapeutic stem cell preparation exert immunomodulatory effects through release of phosphatidylserine

Mesenchymal stem cell (MSC)-mediated immunomodulation has been harnessed for the treatment of human diseases, but its underlying mechanism has not been fully understood. Dead cells, including apoptotic cells have immunomodulatory properties. It has been repeatedly reported that the proportion of non...

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Detalles Bibliográficos
Autores principales: He, Xuemei, Hong, Weiqi, Yang, Jingyun, Lei, Hong, Lu, Tianqi, He, Cai, Bi, Zhenfei, Pan, Xiangyu, Liu, Yu, Dai, Lunzhi, Wang, Wei, Huang, Canhua, Deng, Hongxin, Wei, Xiawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8280232/
https://www.ncbi.nlm.nih.gov/pubmed/34262012
http://dx.doi.org/10.1038/s41392-021-00688-z