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Spontaneous granulocytic leukemia in a NOD/Shi-scid IL-2Rγ(null) mouse

Here, we report a case of spontaneous granulocytic leukemia in a 51-week-old male NOD/Shi-scid IL-2Rγ(null) (NOG) mouse. The mouse showed progressive anemia and rough respiratory movement. Macroscopically, the spleen was discolored and enlarged. Histologically, the bone marrow of the sternum and fem...

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Detalles Bibliográficos
Autores principales: Akane, Hirotoshi, Okuda, Sumiko, Oishi, Yasuaki, Ichikawa, Atsuko, Tabata, Hajime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Toxicologic Pathology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8280305/
https://www.ncbi.nlm.nih.gov/pubmed/34290479
http://dx.doi.org/10.1293/tox.2020-0092