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HILIC–MRM–MS for Linkage-Specific Separation of Sialylated Glycopeptides to Quantify Prostate-Specific Antigen Proteoforms

[Image: see text] Elevated serum prostate-specific antigen (PSA) levels in body fluids may indicate prostate cancer (PCa), but it is noted that the clinical performance is rather poor. Specificity and sensitivity values of 20 and 94% at a cutoff value of 4.1 ng/mL, respectively, result in overdiagno...

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Detalles Bibliográficos
Autores principales: van der Burgt, Yuri E. M., Siliakus, Kasper M., Cobbaert, Christa M., Ruhaak, L. Renee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8280738/
https://www.ncbi.nlm.nih.gov/pubmed/32142289
http://dx.doi.org/10.1021/acs.jproteome.0c00050