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An amphipathic Bax core dimer forms part of the apoptotic pore wall in the mitochondrial␣membrane

Bax proteins form pores in the mitochondrial outer membrane to initiate apoptosis. This might involve their embedding in the cytosolic leaflet of the lipid bilayer, thus generating tension to induce a lipid pore with radially arranged lipids forming the wall. Alternatively, Bax proteins might compri...

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Detalles Bibliográficos
Autores principales: Lv, Fujiao, Qi, Fei, Zhang, Zhi, Wen, Maorong, Kale, Justin, Piai, Alessandro, Du, Lingyu, Wang, Shuqing, Zhou, Liujuan, Yang, Yaqing, Wu, Bin, Liu, Zhijun, del Rosario, Juan, Pogmore, Justin, Chou, James J, Andrews, David W, Lin, Jialing, OuYang, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8280806/
https://www.ncbi.nlm.nih.gov/pubmed/34101209
http://dx.doi.org/10.15252/embj.2020106438