PrimPol‐mediated repriming facilitates replication traverse of DNA interstrand crosslinks

DNA interstrand crosslinks (ICLs) induced by endogenous aldehydes or chemotherapeutic agents interfere with essential processes such as replication and transcription. ICL recognition and repair by the Fanconi Anemia pathway require the formation of an X‐shaped DNA structure that may arise from conve...

Descripción completa

Detalles Bibliográficos
Autores principales: González‐Acosta, Daniel, Blanco‐Romero, Elena, Ubieto‐Capella, Patricia, Mutreja, Karun, Míguez, Samuel, Llanos, Susana, García, Fernando, Muñoz, Javier, Blanco, Luis, Lopes, Massimo, Méndez, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8280817/
https://www.ncbi.nlm.nih.gov/pubmed/34128550
http://dx.doi.org/10.15252/embj.2020106355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8280817/
https://www.ncbi.nlm.nih.gov/pubmed/34128550
http://dx.doi.org/10.15252/embj.2020106355

Ejemplares similares