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Synergic fabrication of pembrolizumab loaded doxorubicin incorporating microbubbles delivery for ultrasound contrast agents mediated anti-proliferation and apoptosis

This study evaluated pembrolizumab-conjugated, doxorubicin (DOX)-loaded microbubbles (PDMs) in combination with ultrasound (US) as molecular imaging agents for early diagnosis of B cell lymphomas, and as a targeted drug delivery system. Pembrolizumab, a monoclonal CD20 antibody, was attached to the...

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Detalles Bibliográficos
Autores principales: Liu, Huilin, Li, Xing, Chen, Zihe, Bai, Lianjie, Wang, Ying, Lv, Weiyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8281080/
https://www.ncbi.nlm.nih.gov/pubmed/34259093
http://dx.doi.org/10.1080/10717544.2021.1921080