Sirt3 promotes the autophagy of HK-2 human proximal tubular epithelial cells via the inhibition of Notch-1/Hes-1 signaling

Diabetic nephropathy (DN) is a predominant cause of end-stage renal disease. The impairment of the autophagy of human renal tubular epithelial cells (HK-2 cells) is involved in the pathogenic mechanisms of DN. Sirtuin (Sirt)3 regulates the scavenging of damaged organelles and maintains energy balanc...

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Detalles Bibliográficos
Autores principales: Wang, Ying, Chang, Jiang, Wang, Zi-Qiang, Li, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8281085/
https://www.ncbi.nlm.nih.gov/pubmed/34278469
http://dx.doi.org/10.3892/mmr.2021.12273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8281085/
https://www.ncbi.nlm.nih.gov/pubmed/34278469
http://dx.doi.org/10.3892/mmr.2021.12273

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