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Lipopolysaccharide Derived From the Lymphoid-Resident Commensal Bacteria Alcaligenes faecalis Functions as an Effective Nasal Adjuvant to Augment IgA Antibody and Th17 Cell Responses

Alcaligenes spp., including A. faecalis, is a gram-negative facultative bacterium uniquely residing inside the Peyer’s patches. We previously showed that A. faecalis-derived lipopolysaccharides (Alcaligenes LPS) acts as a weak agonist of toll-like receptor 4 to activate dendritic cells and shows adj...

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Detalles Bibliográficos
Autores principales: Wang, Yunru, Hosomi, Koji, Shimoyama, Atsushi, Yoshii, Ken, Nagatake, Takahiro, Fujimoto, Yukari, Kiyono, Hiroshi, Fukase, Koichi, Kunisawa, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8281128/
https://www.ncbi.nlm.nih.gov/pubmed/34276692
http://dx.doi.org/10.3389/fimmu.2021.699349