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Folate Deficiency Triggers the Abnormal Segregation of a Region With Large Cluster of CG-Rich Trinucleotide Repeats on Human Chromosome 2

Folate deficiency is associated with a broad range of human disorders, including anemia, fetal neural tube defects, age-associated dementia and several types of cancer. It is well established that a subgroup of rare fragile sites (RFSs) containing expanded CGG trinucleotide repeat (TNR) sequences di...

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Detalles Bibliográficos
Autores principales: Garribba, Lorenza, Vogel, Ivan, Lerdrup, Mads, Gonçalves Dinis, Marisa M., Ren, Liqun, Liu, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8281231/
https://www.ncbi.nlm.nih.gov/pubmed/34276797
http://dx.doi.org/10.3389/fgene.2021.695124