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Folate Deficiency Triggers the Abnormal Segregation of a Region With Large Cluster of CG-Rich Trinucleotide Repeats on Human Chromosome 2
Folate deficiency is associated with a broad range of human disorders, including anemia, fetal neural tube defects, age-associated dementia and several types of cancer. It is well established that a subgroup of rare fragile sites (RFSs) containing expanded CGG trinucleotide repeat (TNR) sequences di...
Autores principales: | Garribba, Lorenza, Vogel, Ivan, Lerdrup, Mads, Gonçalves Dinis, Marisa M., Ren, Liqun, Liu, Ying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8281231/ https://www.ncbi.nlm.nih.gov/pubmed/34276797 http://dx.doi.org/10.3389/fgene.2021.695124 |
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