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Mechanistic Analysis of Age-Related Clinical Manifestations in Down Syndrome

Down syndrome (DS) is the most common genetic cause of Alzheimer’s disease (AD) due to trisomy for all or part of human chromosome 21 (Hsa21). It is also associated with other phenotypes including distinctive facial features, cardiac defects, growth delay, intellectual disability, immune system abno...

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Detalles Bibliográficos
Autores principales: Chen, Xu-Qiao, Xing, Zhuo, Chen, Quang-Di, Salvi, Richard J., Zhang, Xuming, Tycko, Benjamin, Mobley, William C., Yu, Y. Eugene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8281234/
https://www.ncbi.nlm.nih.gov/pubmed/34276349
http://dx.doi.org/10.3389/fnagi.2021.700280