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Oxidative Damage to RNA is Altered by the Presence of Interacting Proteins or Modified Nucleosides

Oxidative stress triggered by the Fenton reaction (chemical) or UVR exposure (photo) can damage cellular biomolecules including RNA through oxidation of nucleotides. Besides such xenobiotic chemical modifications, RNA also contains several post-transcriptional nucleoside modifications that are insta...

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Detalles Bibliográficos
Autores principales: Estevez, Mariana, Valesyan, Satenik, Jora, Manasses, Limbach, Patrick A., Addepalli, Balasubrahmanyam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8281250/
https://www.ncbi.nlm.nih.gov/pubmed/34277707
http://dx.doi.org/10.3389/fmolb.2021.697149