Ligation of newly replicated DNA controls the timing of DNA mismatch repair

Mismatch repair (MMR) safeguards genome stability through recognition and excision of DNA replication errors.(1–4) How eukaryotic MMR targets the newly replicated strand in vivo has not been established. MMR reactions reconstituted in vitro are directed to the strand containing a preexisting nick or...

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Detalles Bibliográficos
Autores principales: Reyes, Gloria X., Kolodziejczak, Anna, Devakumar, Lovely Jael Paul Solomon, Kubota, Takashi, Kolodner, Richard D., Putnam, Christopher D., Hombauer, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8281387/
https://www.ncbi.nlm.nih.gov/pubmed/33417883
http://dx.doi.org/10.1016/j.cub.2020.12.018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8281387/
https://www.ncbi.nlm.nih.gov/pubmed/33417883
http://dx.doi.org/10.1016/j.cub.2020.12.018

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