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CK2-mediated phosphorylation of Che-1/AATF is required for its pro-proliferative activity

BACKGROUND: Che-1/AATF (Che-1) is an RNA polymerase II binding protein involved in several cellular processes, including proliferation, apoptosis and response to stress. We have recently demonstrated that Che-1 is able to promote cell proliferation by sustaining global histone acetylation in multipl...

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Detalles Bibliográficos
Autores principales: Catena, Valeria, Bruno, Tiziana, Iezzi, Simona, Matteoni, Silvia, Salis, Annalisa, Sorino, Cristina, Damonte, Gianluca, Fanciulli, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8281565/
https://www.ncbi.nlm.nih.gov/pubmed/34266450
http://dx.doi.org/10.1186/s13046-021-02038-x