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Transcriptome and genome evolution during HER2-amplified breast neoplasia

BACKGROUND: The acquisition of oncogenic drivers is a critical feature of cancer progression. For some carcinomas, it is clear that certain genetic drivers occur early in neoplasia and others late. Why these drivers are selected and how these changes alter the neoplasia’s fitness is less understood....

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Detalles Bibliográficos
Autores principales: Lu, Peipei, Foley, Joseph, Zhu, Chunfang, McNamara, Katherine, Sirinukunwattana, Korsuk, Vennam, Sujay, Varma, Sushama, Fehri, Hamid, Srivastava, Arunima, Zhu, Shirley, Rittscher, Jens, Mallick, Parag, Curtis, Christina, West, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8281634/
https://www.ncbi.nlm.nih.gov/pubmed/34266469
http://dx.doi.org/10.1186/s13058-021-01451-6