Cargando…

ATF6 aggravates angiogenesis-osteogenesis coupling during ankylosing spondylitis by mediating FGF2 expression in chondrocytes

Although angiogenesis-osteogenesis coupling is important in ankylosing spondylitis (AS), therapeutic agents targeting the vasculature remain elusive. Here, we identified activating transcription factor 6 (ATF6) as an important regulator of angiogenesis in the pathogenesis of AS. First, we found that...

Descripción completa

Detalles Bibliográficos
Autores principales: Ma, Mengjun, Li, Hongyu, Wang, Peng, Yang, Wen, Mi, Rujia, Zhuang, Jiahao, Jiang, Yuhang, Lu, Yixuan, Shen, Xin, Wu, Yanfeng, Shen, Huiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8281657/
https://www.ncbi.nlm.nih.gov/pubmed/34296071
http://dx.doi.org/10.1016/j.isci.2021.102791