Cargando…

ATF6 aggravates angiogenesis-osteogenesis coupling during ankylosing spondylitis by mediating FGF2 expression in chondrocytes

Although angiogenesis-osteogenesis coupling is important in ankylosing spondylitis (AS), therapeutic agents targeting the vasculature remain elusive. Here, we identified activating transcription factor 6 (ATF6) as an important regulator of angiogenesis in the pathogenesis of AS. First, we found that...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ma, Mengjun, Li, Hongyu, Wang, Peng, Yang, Wen, Mi, Rujia, Zhuang, Jiahao, Jiang, Yuhang, Lu, Yixuan, Shen, Xin, Wu, Yanfeng, Shen, Huiyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8281657/ https://www.ncbi.nlm.nih.gov/pubmed/34296071 http://dx.doi.org/10.1016/j.isci.2021.102791

Ejemplares similares

SMAD‐specific E3 ubiquitin ligase 2 promotes angiogenesis by facilitating PTX3 degradation in MSCs from patients with ankylosing spondylitis
por: Ma, Mengjun, et al.
Publicado: (2021)

ZIP10 drives osteosarcoma proliferation and chemoresistance through ITGA10-mediated activation of the PI3K/AKT pathway
por: Li, Hongyu, et al.
Publicado: (2021)

Targeting chondrocytes for arresting bony fusion in ankylosing spondylitis
por: Shao, Fenli, et al.
Publicado: (2021)

Abnormal inhibition of osteoclastogenesis by mesenchymal stem cells through the miR-4284/CXCL5 axis in ankylosing spondylitis
por: Liu, Wenjie, et al.
Publicado: (2019)

Whole Genome Expression Profiling and Signal Pathway Screening of MSCs in Ankylosing Spondylitis
por: Li, Yuxi, et al.
Publicado: (2014)

Increased BMPR1A Expression Enhances the Adipogenic Differentiation of Mesenchymal Stem Cells in Patients with Ankylosing Spondylitis
por: Liu, Zhenhua, et al.
Publicado: (2019)

Ankylosing spondylitis
Publicado: (1980)

Ankylosing spondylitis
por: Edavalath, Mukesh
Publicado: (2010)

Ankylosing Spondylitis
por: Whitfield, A. G. W.
Publicado: (1976)

Ankylosing Spondylitis
por: Ebrahimiadib, Nazanin, et al.
Publicado: (2021)

Sacroiliitis and Spondylitis with Sternoclavicular Hyperostosis: SAPHO or an Ankylosing Spondylitis Variant?
por: Shen, Kai, et al.
Publicado: (2016)

Oxidative stress-mediated mitochondrial dysfunction facilitates mesenchymal stem cell senescence in ankylosing spondylitis
por: Ye, Guiwen, et al.
Publicado: (2020)

All-Trans Retinoic Acid Improves the Effects of Bone Marrow-Derived Mesenchymal Stem Cells on the Treatment of Ankylosing Spondylitis: An In Vitro Study
por: Li, Deng, et al.
Publicado: (2015)

The Role of MicroRNAS in Ankylosing Spondylitis
por: Li, Zheng, et al.
Publicado: (2016)

Advances in nanomedicine for the treatment of ankylosing spondylitis
por: Xi, Yanhai, et al.
Publicado: (2019)

Noncoding RNAs Involved in the Pathogenesis of Ankylosing Spondylitis
por: Chen, Chong, et al.
Publicado: (2019)

Imaging of ankylosing spondylitis
por: Østergaard, Mikkel
Publicado: (2012)

Alexithymia in ankylosing spondylitis
por: Karabıçak, Deniz, et al.
Publicado: (2021)

Elevated TRAF4 expression impaired LPS-induced autophagy in mesenchymal stem cells from ankylosing spondylitis patients
por: Li, Jinteng, et al.
Publicado: (2017)

TNF-α Induced the Enhanced Apoptosis of Mesenchymal Stem Cells in Ankylosing Spondylitis by Overexpressing TRAIL-R2
por: Liu, Zhenhua, et al.
Publicado: (2017)

MYC promotes fibroblast osteogenesis by regulating ALP and BMP2 to participate in ectopic ossification of ankylosing spondylitis
por: Jin, Qianmei, et al.
Publicado: (2023)

A new and spontaneous animal model for ankylosing spondylitis is found in cynomolgus monkeys
por: Jia, Huanhuan, et al.
Publicado: (2022)

RNA Sequencing Reveals the Expression Profiles of circRNAs and Indicates Hsa_circ_0070562 as a Pro-osteogenic Factor in Bone Marrow-Derived Mesenchymal Stem Cells of Patients With Ankylosing Spondylitis
por: Wang, Shan, et al.
Publicado: (2022)

Rotating Magnetic Field Mitigates Ankylosing Spondylitis Targeting Osteocytes and Chondrocytes via Ameliorating Immune Dysfunctions
por: Han, Yu, et al.
Publicado: (2023)

Enhanced osteogenic differentiation of mesenchymal stem cells in ankylosing spondylitis: a study based on a three-dimensional biomimetic environment
por: Zheng, Guan, et al.
Publicado: (2019)

Up‐regulation of TβRIII facilitates the osteogenesis of supraspinous ligament‐derived fibroblasts from patients with ankylosing spondylitis
por: Zhang, Ying, et al.
Publicado: (2021)

Update on the treatment of ankylosing spondylitis
por: Maksymowych, Walter P
Publicado: (2007)

Ankylosing spondylitis: yesterday and today.
por: Spencer, D G, et al.
Publicado: (1980)

Treat Ankylosing Spondylitis with Methazolamide
por: Chang, Xiaotian, et al.
Publicado: (2011)

Infliximab in the treatment of ankylosing spondylitis
por: Grainger, Rebecca, et al.
Publicado: (2007)

Ankylosing Spondylitis and Cardiac Abnormalities
por: Yang, Dong Heon
Publicado: (2012)

Cardiopulmonary Manifestations of Ankylosing Spondylitis
por: Momeni, Mahnaz, et al.
Publicado: (2011)

Spinal instability in ankylosing spondylitis
por: Badve, Siddharth A, et al.
Publicado: (2010)

Microbes, the gut and ankylosing spondylitis
por: Costello, Mary-Ellen, et al.
Publicado: (2013)

Advances in managing ankylosing spondylitis
por: Daikh, David I., et al.
Publicado: (2014)

Trends of Ankylosing Spondylitis Ossification
por: Rozin, Alexander P
Publicado: (2013)

Cardiac Involvement in Ankylosing Spondylitis
por: Ozkan, Yasemin
Publicado: (2016)

Predictors of Atherosclerosis in Ankylosing Spondylitis
por: Verma, Inderjeet, et al.
Publicado: (2015)

Medical Treatment of Ankylosing Spondylitis
por: Moon, Kyoung-Ho, et al.
Publicado: (2014)

Management of ankylosing spondylitis with infliximab
por: Toussirot, Éric, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_3en3ooectv8c64mheta7hgo5oa