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Ten-gene signature reveals the significance of clinical prognosis and immuno-correlation of osteosarcoma and study on novel skeleton inhibitors regarding MMP9

OBJECTIVES: This study aimed to identify novel targets in the carcinogenesis, therapy and prognosis of osteosarcoma from genomic level, together with screening ideal lead compounds with potential inhibition regarding MMP-9. METHODS: Gene expression profiles from GSE12865, GSE14359, GSE33382, GSE3600...

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Detalles Bibliográficos
Autores principales: Li, Weihang, Ding, Ziyi, Wang, Dong, Li, Chengfei, Pan, Yikai, Zhao, Yingjing, Zhao, Hongzhe, Lu, Tianxing, Xu, Rui, Zhang, Shilei, Yuan, Bin, Zhao, Yunlong, Yin, Yanjiang, Gao, Yuan, Li, Jing, Yan, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8281696/
https://www.ncbi.nlm.nih.gov/pubmed/34261456
http://dx.doi.org/10.1186/s12935-021-02041-4