Crosstalk Between DNA Methylation and Gene Mutations in Colorectal Cancer

Colorectal cancer (CRC) is often characterized by mutations and aberrant DNA methylation within the promoters of tumor suppressor genes and proto-oncogenes. The most frequent somatic mutations occur within KRAS and BRAF genes. Mutations of the KRAS gene have been detected in approximately 40% of pat...

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Detalles Bibliográficos
Autores principales: Dobre, Maria, Salvi, Alessandro, Pelisenco, Iulia Andreea, Vasilescu, Florina, De Petro, Giuseppina, Herlea, Vlad, Milanesi, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8281955/
https://www.ncbi.nlm.nih.gov/pubmed/34277443
http://dx.doi.org/10.3389/fonc.2021.697409

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8281955/
https://www.ncbi.nlm.nih.gov/pubmed/34277443
http://dx.doi.org/10.3389/fonc.2021.697409

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