Cargando…

Crosstalk Between DNA Methylation and Gene Mutations in Colorectal Cancer

Colorectal cancer (CRC) is often characterized by mutations and aberrant DNA methylation within the promoters of tumor suppressor genes and proto-oncogenes. The most frequent somatic mutations occur within KRAS and BRAF genes. Mutations of the KRAS gene have been detected in approximately 40% of pat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dobre, Maria, Salvi, Alessandro, Pelisenco, Iulia Andreea, Vasilescu, Florina, De Petro, Giuseppina, Herlea, Vlad, Milanesi, Elena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8281955/ https://www.ncbi.nlm.nih.gov/pubmed/34277443 http://dx.doi.org/10.3389/fonc.2021.697409

Ejemplares similares

miRNAs-Based Molecular Signature for KRAS Mutated and Wild Type Colorectal Cancer: An Explorative Study
por: Milanesi, Elena, et al.
Publicado: (2020)

Lipid Handling Protein Gene Expression in Colorectal Cancer: CD36 and Targeting miRNAs
por: Niculae, Andrei Marian, et al.
Publicado: (2022)

Molecular profile of the NF‐κB signalling pathway in human colorectal cancer
por: Dobre, Maria, et al.
Publicado: (2022)

Let-7 microRNAs Are Possibly Associated with Perineural Invasion in Colorectal Cancer by Targeting IGF Axis
por: Niculae, Andrei Marian, et al.
Publicado: (2022)

Dysregulation of miRNAs Targeting the IGF-1R Pathway in Pancreatic Ductal Adenocarcinoma
por: Dobre, Maria, et al.
Publicado: (2021)

Increased Levels of miR-15b-5p and miR-20b-5p in Pancreatic Ductal Adenocarcinoma with Hepatic Metastases
por: Dobre, Maria, et al.
Publicado: (2023)

Crosstalk between enteric serotonergic neurons and colorectal cancer stem cells to initiate colorectal tumorigenesis
por: Jia, Jiamei, et al.
Publicado: (2022)

DNA methylation-based patterns for early diagnostic prediction and prognostic evaluation in colorectal cancer patients with high tumor mutation burden
por: Huang, Hao, et al.
Publicado: (2023)

Fecal Multidimensional Assay for Non-Invasive Detection of Colorectal Cancer: Fecal Immunochemical Test, Stool DNA Mutation, Methylation, and Intestinal Bacteria Analysis
por: Mo, Shaobo, et al.
Publicado: (2021)

DNA methylation variations in familial female and male breast cancer
por: Abeni, Edoardo, et al.
Publicado: (2021)

Coordinate to Guard: Crosstalk of Phosphorylation, Sumoylation, and Ubiquitylation in DNA Damage Response
por: Kuo, Ching-Ying, et al.
Publicado: (2012)

Mutation analysis by direct and whole exome sequencing in familial and sporadic tooth agenesis
por: Salvi, Alessandro, et al.
Publicado: (2016)

A novel DNA methylation marker to identify lymph node metastasis of colorectal cancer
por: Yu, Yingdian, et al.
Publicado: (2022)

Pancreatic Fistula after D1+/D2 Radical Gastrectomy according to the Updated International Study Group of Pancreatic Surgery Criteria: Risk Factors and Clinical Consequences. Experience of Surgeons with High Caseloads in a Single Surgical Center in Eastern Europe
por: Martiniuc, Alexandru, et al.
Publicado: (2021)

Sorafenib induces variations of the DNA methylome in HA22T/VGH human hepatocellular carcinoma-derived cells
por: Abeni, Edoardo, et al.
Publicado: (2017)

KRAS Mutational Regression Is Associated With Oligo-Metastatic Status and Good Prognosis in Metastatic Colorectal Cancer
por: Ottaiano, Alessandro, et al.
Publicado: (2021)

Metabolic Plasticity of Melanoma Cells and Their Crosstalk With Tumor Microenvironment
por: Avagliano, Angelica, et al.
Publicado: (2020)

KCNQ5 and C9orf50 Methylation in Stool DNA for Early Detection of Colorectal Cancer
por: Cao, Yaping, et al.
Publicado: (2021)

Four methylation-driven genes detected by linear discriminant analysis model from early-stage colorectal cancer and their methylation levels in cell-free DNA
por: Zhan, Lei, et al.
Publicado: (2022)

Seven DNA Methylation Biomarker Prediction Models for Monitoring the Malignant Progression From Advanced Adenoma to Colorectal Cancer
por: Wang, Wei, et al.
Publicado: (2022)

Correlation Between Pretreatment Neutrophil-to-Lymphocyte Ratio and Programmed Death-Ligand 1 Expression as Prognostic Markers in Non-Small Cell Lung Cancer
por: Pirlog, Cristina-Florina, et al.
Publicado: (2022)

The seen and the unseen: Molecular classification and image based-analysis of gastrointestinal cancers
por: Minciuna, Corina-Elena, et al.
Publicado: (2022)

Positive Crosstalk Between Hedgehog and NF-κB Pathways Is Dependent on KRAS Mutation in Pancreatic Ductal Adenocarcinoma
por: Wang, Yuqiong, et al.
Publicado: (2021)

Mutated DNA Damage Repair Pathways Are Prognostic and Chemosensitivity Markers for Resected Colorectal Cancer Liver Metastases
por: Wang, Kun, et al.
Publicado: (2021)

Lasp1 Expression Is Implicated in Embryonic Development of Zebrafish
por: Grossi, Ilaria, et al.
Publicado: (2022)

High Circulating Methylated DNA Is a Negative Predictive and Prognostic Marker in Metastatic Colorectal Cancer Patients Treated With Regorafenib
por: Amatu, Alessio, et al.
Publicado: (2019)

Editorial: The Treatment of RAS or BRAF Mutated Metastatic Colorectal Cancer: Challenges and Perspectives
por: Ottaiano, Alessandro, et al.
Publicado: (2022)

The Biological Role and Translational Implications of the Long Non-Coding RNA GAS5 in Breast Cancer
por: Grossi, Ilaria, et al.
Publicado: (2023)

Mutation Detection in Tumor-Derived Cell Free DNA Anticipates Progression in a Patient With Metastatic Colorectal Cancer
por: de Figueiredo Barros, Bruna D., et al.
Publicado: (2018)

Colorectal Cancer: Molecular Mutations and Polymorphisms
por: Sameer, Aga Syed
Publicado: (2013)

Combined Positive Score for Programmed Death Ligand-1 Expression and Inflammatory Microenvironment in Gastrointestinal Stromal Tumors
por: Herlea, Vlad, et al.
Publicado: (2022)

DNA Methylation Targeting: The DNMT/HMT Crosstalk Challenge
por: Castillo-Aguilera, Omar, et al.
Publicado: (2017)

Crosstalk between miRNAs and DNA Methylation in Cancer
por: Saviana, Michela, et al.
Publicado: (2023)

Why the Therapeutic Impact of RAS Mutation Clearance in Plasma ctDNA Deserves to Be Further Explored in Metastatic Colorectal Cancer
por: Nicolazzo, Chiara, et al.
Publicado: (2019)

DNA Damage Repair Gene Mutations Are Indicative of a Favorable Prognosis in Colorectal Cancer Treated With Immune Checkpoint Inhibitors
por: Song, Yipeng, et al.
Publicado: (2021)

Blood Cell DNA Methylation of Aging-Related Ubiquitination Gene DZIP3 Can Predict the Onset of Early Stage Colorectal Cancer
por: Quan, Yuan, et al.
Publicado: (2020)

Combining methylated SDC2 test in stool DNA, fecal immunochemical test, and tumor markers improves early detection of colorectal neoplasms
por: Zeng, Tao, et al.
Publicado: (2023)

Diagnostic Value of Methylated Septin9 for Colorectal Cancer Detection
por: Xie, Li, et al.
Publicado: (2018)

Crosstalk Between MYC and lncRNAs in Hematological Malignancies
por: Arman, Kaifee, et al.
Publicado: (2020)

Metabolic Reprogramming of Thyroid Cancer Cells and Crosstalk in Their Microenvironment
por: Bao, Lisha, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_gb77f3fj0pjrsco88o4nh834nq