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The mTOR–Autophagy Axis and the Control of Metabolism

The mechanistic target of rapamycin (mTOR), master regulator of cellular metabolism, exists in two distinct complexes: mTOR complex 1 and mTOR complex 2 (mTORC1 and 2). MTORC1 is a master switch for most energetically onerous processes in the cell, driving cell growth and building cellular biomass i...

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Detalles Bibliográficos
Autores principales: Deleyto-Seldas, Nerea, Efeyan, Alejo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8281972/
https://www.ncbi.nlm.nih.gov/pubmed/34277603
http://dx.doi.org/10.3389/fcell.2021.655731