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Infectious titer determination of lentiviral vectors using a temporal immunological real-time imaging approach

The analysis of the infectious titer of the lentiviral vector samples obtained during upstream and downstream processing is of major importance, however, also the most challenging method to be performed. Currently established methods like flow cytometry or qPCR lack the capability of enabling high t...

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Detalles Bibliográficos
Autores principales: Labisch, Jennifer J., Wiese, G. Philip, Barnes, Kalpana, Bollmann, Franziska, Pflanz, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8281989/
https://www.ncbi.nlm.nih.gov/pubmed/34265014
http://dx.doi.org/10.1371/journal.pone.0254739