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Metformin intervention ameliorates AS in ApoE(-/-) mice through restoring gut dysbiosis and anti-inflammation

Atherosclerosis (AS) is closely associated with chronic low-grade inflammation and gut dysbiosis. Metformin (MET) presents pleiotropic benefits in the control of chronic metabolic diseases, but the impacts of MET intervention on gut microbiota and inflammation in AS remain largely unclear. In this s...

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Detalles Bibliográficos
Autores principales: Yan, Ning, Wang, Lijuan, Li, Yiwei, Wang, Ting, Yang, Libo, Yan, Ru, Wang, Hao, Jia, Shaobin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282009/
https://www.ncbi.nlm.nih.gov/pubmed/34264978
http://dx.doi.org/10.1371/journal.pone.0254321