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High-molecular weight DNA extraction, clean-up and size selection for long-read sequencing

Rapid advancements in long-read sequencing technologies have transformed read lengths from bps to Mbps, which has enabled chromosome-scale genome assemblies. However, read lengths are now becoming limited by the extraction of pure high-molecular weight DNA suitable for long-read sequencing, which is...

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Detalles Bibliográficos
Autores principales: Jones, Ashley, Torkel, Cynthia, Stanley, David, Nasim, Jamila, Borevitz, Justin, Schwessinger, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282028/
https://www.ncbi.nlm.nih.gov/pubmed/34264958
http://dx.doi.org/10.1371/journal.pone.0253830