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Pre-vaccination and early B cell signatures predict antibody response to SARS-CoV-2 mRNA vaccine

SARS-CoV-2 mRNA vaccines are highly effective, although weak antibody responses are seen in some individuals with correlates of immunity that remain poorly understood. Here we longitudinally dissected antibody, plasmablast, and memory B cell (MBC) responses to the two-dose Moderna mRNA vaccine in SA...

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Detalles Bibliográficos
Autores principales: Kardava, Lela, Rachmaninoff, Nicholas, Lau, William W., Buckner, Clarisa M., Trihemasava, Krittin, de Assis, Felipe Lopes, Wang, Wei, Zhang, Xiaozhen, Wang, Yimeng, Chiang, Chi-I, Narpala, Sandeep, Reger, Robert, McCormack, Genevieve E., Seamon, Catherine A., Childs, Richard W., Suffredini, Anthony F., Strich, Jeffrey R., Chertow, Daniel S., Davey, Richard T., Sneller, Michael C., O’Connell, Sarah, Li, Yuxing, McDermott, Adrian, Chun, Tae-Wook, Fauci, Anthony S., Tsang, John S., Moir, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282109/
https://www.ncbi.nlm.nih.gov/pubmed/34268520
http://dx.doi.org/10.1101/2021.07.06.21259528