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Persistent Metabolic Effects of Tamoxifen: Considerations for an Experimental Tool and Clinical Breast Cancer Treatment

The selective estrogen receptor (ER) modulator tamoxifen is frequently used in preclinical studies to induce Cre recombinase and generate conditional transgenic mice. In addition, it is often prescribed to treat ER-positive breast cancer, which is diagnosed in approximately 150 000 people each year....

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Detalles Bibliográficos
Autores principales: Stout, Michael B, Scalzo, Rebecca L, Wellberg, Elizabeth A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282119/
https://www.ncbi.nlm.nih.gov/pubmed/34161568
http://dx.doi.org/10.1210/endocr/bqab126