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Approaches for Controlling Antibody-Mediated Allograft Rejection Through Targeting B Cells

Both acute and chronic antibody-mediated allograft rejection (AMR), which are directly mediated by B cells, remain difficult to treat. Long-lived plasma cells (LLPCs) in bone marrow (BM) play a crucial role in the production of the antibodies that induce AMR. However, LLPCs survive through a T cell-...

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Detalles Bibliográficos
Autores principales: Matsuda, Yoshiko, Watanabe, Takeshi, Li, Xiao-Kang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282180/
https://www.ncbi.nlm.nih.gov/pubmed/34276669
http://dx.doi.org/10.3389/fimmu.2021.682334