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Approaches for Controlling Antibody-Mediated Allograft Rejection Through Targeting B Cells
Both acute and chronic antibody-mediated allograft rejection (AMR), which are directly mediated by B cells, remain difficult to treat. Long-lived plasma cells (LLPCs) in bone marrow (BM) play a crucial role in the production of the antibodies that induce AMR. However, LLPCs survive through a T cell-...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282180/ https://www.ncbi.nlm.nih.gov/pubmed/34276669 http://dx.doi.org/10.3389/fimmu.2021.682334 |