Alterations in mitochondrial dynamics with age‐related Sirtuin1/Sirtuin3 deficiency impair cardiomyocyte contractility

Sirtuin1 (SIRT1) and Sirtuin3 (SIRT3) protects cardiac function against ischemia/reperfusion (I/R) injury. Mitochondria are critical in response to myocardial I/R injury as disturbance of mitochondrial dynamics contributes to cardiac dysfunction. It is hypothesized that SIRT1 and SIRT3 are critical...

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Detalles Bibliográficos
Autores principales: Zhang, Jingwen, He, Zhibin, Fedorova, Julia, Logan, Cole, Bates, Lauryn, Davitt, Kayla, Le, Van, Murphy, Jiayuan, Li, Melissa, Wang, Mingyi, Lakatta, Edward G., Ren, Di, Li, Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282250/
https://www.ncbi.nlm.nih.gov/pubmed/34216536
http://dx.doi.org/10.1111/acel.13419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282250/
https://www.ncbi.nlm.nih.gov/pubmed/34216536
http://dx.doi.org/10.1111/acel.13419

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